TOLNAFTATE USP
TOLNAFTATE USP
TOLNAFTATE USP
Molecular Formula: C19H17NOS
Molecular Weight : 307.4
CAS No. : [2398 – 96 – 1]
Application:
Antifungal
General properties:
Physical Form:
White to creamy white, fine powder, having a slight odour.
Physiochemical Properties:
White to creamy white, fine powder, with a slight odour. Having melting range between
110°C and 113°C.
SPECIFICATION FOR CHLORPHENESIN BP
| Sr. No. | Tests | Specification |
|---|---|---|
| 1 | DESCRIPTION | White to creamy white, fine powder, having a slight odour. |
| 2 | SOLUBILITY | Freely soluble in acetone and in chloroform, sparingly soluble in ether, slightly soluble in alcohol. Practically insoluble in water. |
| 3 | IDENTIFICATION A) IR B) UV C) TLC | The Infra-Red spectrum of the sample is concordant with that of Tolnaftate std. The UV absorbance spectrum of the sample solution exhibits maxima and minima at the same wavelength as that of a similar solution of Tolnaftate standard. The RF value of the principal spot obtained from the test solution corresponds to that obtained from the std solution. |
| 4 | MELTING RANGE | Between 110°C and 113°C. |
| 5 | LOSS ON DRYING | Not more than 0.5% |
| 6 | RESIDUE ON IGNITION | Not more than 0.1% |
| 7 | ASSAY (On dried Basis) | Not less than 98.0% and not more than 102.0% |