MICONAZOLE EP

Molecular Formula: C18H14Cl4N2O
Molecular Weight : 416.1g/Mol

CAS No. : [22916-47-8]

Application:

Anti-Fungal Azole

General properties:

White or almost white powder.

Sr. No.	Tests	Specification
1	DESCRIPTION	White or almost white powder.
2	SOLUBILITY	Very slightly soluble in water, freely soluble in methanol, soluble in ethanol (96%).
3	IDENTIFICATION A] MELTING POINT B] IR C] MELTING POINT D] CHLORIDES	First Identification A, B. Second Identification C, D. 83°C TO 87°C The Infra-Red spectrum of the sample is concordant with that of Miconazole WS. Result A 83°C TO 87°C Result B The absolute difference between the melting point of the mixture and the value obtained in determination A is not greater 2°C. It gives reaction of Chlorides.
4	APPEARANCE OF SOLUTION	Dissolve 0.1g in Methanol R & dilute to 10.0 ml with the same solvent. Solution S Solution S is clear and not more intensely coloured than reference solution Y6.
5	OPTICAL ROTATION	-0.10° to + 0.10° of solution S
6	RELATED SUBSTANCES IMPURITY A IMPURITY B IMPURITY C IMPURITY D IMPURITY E IMPURITY F IMPURITY G UNSPECIFIED IMPURITY TOTAL IMPURITIES	Not more than 0.10% Not more than 0.10% Not more than 0.10% Not more than 0.10% Not more than 0.10% Not more than 0.10% Not more than 0.10% Not more than 0.10% Not more than 0.30%
7	LOSS ON DRYING	Not more than 0.5%
8	SULPHATED ASH	Not more than 0.1 %
9	ASSAY (On Dried Basis)	Not less than 99.0%

Storage condition: store in a well closed container.
Safety. Environment. Regulation: Refer to MSDS of MICONAZOLE EP